Monoclonal antibody treatment has emerged as a relatively effective and safer alternative in treating COVID-19 patients.
- As per the statement of the doctors, as with any other drug, timing is very important for the administration of the therapy that’s touted as a game-changer.
- Monoclonal antibodies have previously been used to treat infections such as Ebola and HIV.
- The therapy is now said to help avoid hospitalization in high-risk groups, progression to severe disease, and to reduce the usage of steroids.
- However, doctors claim that though the method does not cure the infection. The treatment helps in preventing the development of Covid-19 severity among mild to moderately infected patients with severe comorbidities if administered within seven days of the infection.
Immune response of antibodies in human beings:
- Antibodies produced naturally in bodies fight against diseases.
- The body’s immune system generates antibodies as a defense mechanism against unfamiliar molecules from bacteria and viruses, termed antigens.
- Antibodies bind to antigens and kill the invading pathogen.
Monoclonal antibody treatment:
- Monoclonal antibodies too, work similarly as the naturally produced antibodies in a human body, but these are made artificially in a laboratory that helps in defending against the disease.
- The Monoclonal antibodies help in reducing the symptoms and disease progression.
- These antibodies have previously been used to treat viral infections such as Ebola and HIV.
- Two of the Monoclonal antibodies being used in India include the REGCov2 (Casirivimab and Imdevimab).
- In these drugs, antibodies for COVID target specific proteins and destroy them before they initiate inflammation.
What are Monoclonal antibodies?
- Monoclonal antibodies are identical copies of an antibody that targets one specific antigen.
- Scientists can make monoclonal antibodies by exposing white blood cells to a particular antigen.
- Each monoclonal antibody is specific to its matching antigen.
- Scientists select a single white blood cell or clone and use this as the basis to produce many identical cells, making many identical copies of the monoclonal antibody.